Why were sarms created

by Roger Whitham

Selective Androgen Receptor Modulators (SARMs) were initially developed to address conditions like muscle wasting, osteoporosis, and other disorders associated with muscle and bone loss. The goal was to create compounds that could selectively target and activate androgen receptors in specific tissues, such as muscles and bones, while minimizing the impact on other organs, which is a common issue with traditional anabolic steroids.

While SARMs are still under investigation and not approved for medical use, some have progressed to clinical trials. Here's a brief overview of several types of SARMs and their purported effects based on research:

  1. Ostarine (MK-2866):

    • Purpose: Ostarine is designed to prevent and treat muscle wasting.
    • Research: Studies suggest potential benefits in increasing lean muscle mass and improving physical function without the adverse effects associated with traditional anabolic steroids.

  2. Ligandrol (LGD-4033):

    • Purpose: Ligandrol is developed to combat muscle wasting and promote muscle growth.
    • Research: It has shown promise in increasing muscle mass and strength, with some studies indicating positive effects on bone health as well.

  3. Andarine (S-4):

    • Purpose: Andarine was developed for muscle wasting and osteoporosis.
    • Research: Research indicates its potential in promoting muscle mass and improving bone density.

  4. Cardarine (GW-501516):

    • Purpose: Cardarine was initially designed to treat metabolic and cardiovascular diseases.
    • Research: It has been studied for its potential benefits in improving endurance and metabolic health, but concerns have been raised about its safety, leading to discontinuation of clinical trials.

  5. RAD140 (Testolone):

    • Purpose: RAD140 is developed to counteract muscle wasting disorders and conditions like breast cancer.
    • Research: Studies suggest potential benefits in increasing muscle mass and improving physical performance.

It's important to note that while SARMs show promise in the field of muscle and bone health, their safety, long-term effects, and potential for misuse are still under investigation. Additionally, the regulatory status of SARMs varies, and they are not approved for medical use in many regions. Always consult with healthcare professionals for accurate and up-to-date information.

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